ECG for high-throughput screening of multiple diseases: Proof-of-concept using multi-diagnosis deep learning from population-based datasets

Weijie Sun, Sunil Vasu Kalmady, Amir S Salimi, Nariman Sepehrvand, Eric Ly, Abram Hindle, Russell Greiner, Padma Kaul

2021/10/26

ECG for high-throughput screening of multiple diseases: Proof-of-concept using multi-diagnosis deep learning from population-based datasets

Authors

Weijie Sun, Sunil Vasu Kalmady, Amir S Salimi, Nariman Sepehrvand, Eric Ly, Abram Hindle, Russell Greiner, Padma Kaul

Venue

Abstract

Electrocardiogram (ECG) abnormalities are linked to cardiovascular diseases, but may also occur in other non-cardiovascular conditions such as mental, neurological, metabolic and infectious conditions. However, most of the recent success of deep learning (DL) based diagnostic predictions in selected patient cohorts have been limited to a small set of cardiac diseases. In this study, we use a population-based dataset of >250,000 patients with >1000 medical conditions and >2 million ECGs to identify a wide range of diseases that could be accurately diagnosed from the patient’s first in-hospital ECG. Our DL models uncovered 128 diseases and 68 disease categories with strong discriminative performance.

Bibtex

@inproceedings{sun2021NEURIPS-ECG-screening,
 abstract = {Electrocardiogram (ECG) abnormalities are linked to cardiovascular diseases, but may also occur in other non-cardiovascular conditions such as mental, neurological, metabolic and infectious conditions. However, most of the recent success of deep learning (DL) based diagnostic predictions in selected patient cohorts have been limited to a small set of cardiac diseases. In this study, we use a population-based dataset of >250,000 patients with >1000 medical conditions and >2 million ECGs to identify a wide range of diseases that could be accurately diagnosed from the patient’s first in-hospital ECG. Our DL models uncovered 128 diseases and 68 disease categories with strong discriminative performance.},
 accepted = {2021-10-26},
 author = {Weijie Sun and Sunil Vasu Kalmady and Amir S Salimi and Nariman Sepehrvand and Eric Ly and Abram Hindle and Russell Greiner and Padma Kaul},
 authors = {Weijie Sun, Sunil Vasu Kalmady, Amir S Salimi, Nariman Sepehrvand, Eric Ly, Abram Hindle, Russell Greiner, Padma Kaul},
 booktitle = {Medical Imaging Workshop at NeurIPS},
 code = {sun2021NEURIPS-ECG-screening},
 date = {2021-12-14},
 funding = {NSERC Discovery and CVC},
 location = {Online},
 pagerange = {1--6},
 pages = {1--6},
 rate = {56/90},
 role = {Co-Author},
 title = {ECG for high-throughput screening of multiple diseases: Proof-of-concept using multi-diagnosis deep learning from population-based datasets},
 type = {inproceedings},
 url = {http://softwareprocess.ca/pubs/sun2021NEURIPS-ECG-screening.pdf},
 venue = {Medical Imaging Workshop at NeurIPS},
 year = {2021}
}