Improving ECG-based COVID-19 diagnosis and mortality predictions using pre-pandemic medical records at population-scale

Weijie Sun and Sunil Vasu Kalmady and Zihan Wang and Amir Salimi and Nariman Sepehrvand and Abram Hindle and Luan Manh Chu and Russell Greiner and Padma Kaul

2022/01/01

Improving ECG-based COVID-19 diagnosis and mortality predictions using pre-pandemic medical records at population-scale

Authors

Weijie Sun and Sunil Vasu Kalmady and Zihan Wang and Amir Salimi and Nariman Sepehrvand and Abram Hindle and Luan Manh Chu and Russell Greiner and Padma Kaul

Venue

Abstract

Pandemic outbreaks such as COVID-19 occur unexpectedly, and need immediate action due to their potential devastating consequences on global health. Point-of-care routine assessments such as electrocardiogram (ECG), can be used to develop prediction models for identifying individuals at risk. However, there is often too little clinically-annotated medical data, especially in early phases of a pandemic, to develop accurate prediction models. In such situations, historical pre-pandemic health records can be utilized to estimate a preliminary model, which can then be fine-tuned based on limited available pandemic data. This study shows this approach – pre-train deep learning models with pre-pandemic data – can work effectively, by demonstrating substantial performance improvement over three different COVID-19 related diagnostic and prognostic prediction tasks. Similar transfer learning strategies can be useful for developing timely artificial intelligence solutions in future pandemic outbreaks.

Bibtex

@inproceedings{sun2022TS4H-improving-ecg-covid,
 abstract = {Pandemic outbreaks such as COVID-19 occur unexpectedly, and need immediate action due to their potential devastating consequences on global health. Point-of-care routine assessments such as electrocardiogram (ECG), can be used to develop prediction models for identifying individuals at risk. However, there is often too little clinically-annotated medical data, especially in early phases of a pandemic, to develop accurate prediction models. In such situations, historical pre-pandemic health records can be utilized to estimate a preliminary model, which can then be fine-tuned based on limited available pandemic data. This study shows this approach – pre-train deep learning models with pre-pandemic data – can work effectively, by demonstrating substantial performance improvement over three different COVID-19 related diagnostic and prognostic prediction tasks. Similar transfer learning strategies can be useful for developing timely artificial intelligence solutions in future pandemic outbreaks.},
 author = {Weijie Sun and Sunil Vasu Kalmady and Zihan Wang and Amir Salimi and Nariman Sepehrvand and Abram Hindle and Luan Manh Chu and Russell Greiner and Padma Kaul},
 authors = {Weijie Sun and Sunil Vasu Kalmady and Zihan Wang and Amir Salimi and Nariman Sepehrvand and Abram Hindle and Luan Manh Chu and Russell Greiner and Padma Kaul},
 booktitle = {NeurIPS TS4H: Timeseries for Health},
 code = {sun2022TS4H-improving-ecg-covid},
 funding = {NSERC Discovery},
 location = {New Orleans, United States},
 pages = {1--9},
 rate = {Unknown},
 role = {Co-Author},
 title = {Improving ECG-based COVID-19 diagnosis and mortality predictions using pre-pandemic medical records at population-scale},
 type = {inproceedings},
 url = {http://softwareprocess.ca/pubs/sun2022TS4H-improving-ecg-covid.pdf},
 venue = {NeurIPS TS4H: Timeseries for Health},
 year = {2022}
}